Selected publications


Recent:

2020

  • Hazari Y, Bravo-San Pedro JM, Hetz C, Galluzzi L, Kroemer G. Autophagy in hepatic adaptation to stress. J Hepatol. 2020 Jan;72(1):183-196.
  • Pol JG, Caudana P, Paillet J, Piaggio E, Kroemer G. Effects of interleukin-2 in immunostimulation and immunosuppression. J Exp Med. 2019 Oct 14. pii: jem.20191247. doi: 10.1084/jem.20191247. [Epub ahead of print] 
  • Kepp O, Marabelle A, Zitvogel L, Kroemer G. Oncolysis without viruses -  inducing systemic anticancer immune responses with local therapies. Nat Rev Clin Oncol. 2020 Jan;17(1):49-64
  • Liu P, Zhao L, Loos F, Marty C, Xie W, Martins I, Lachkar S, Qu B, Waeckel-Enée E, Plo I, Perez F, Lopez-Otin C, van Endert P, Zitvogel L, Kepp O, Kroemer G. Immunosuppression by mutated calreticulin released from malignant cells. Mol CellIn press
  • Dufey E, Bravo-San Pedro J, Eggers C, Gonzalez-Quiros M, Urra H, Sepulveda D, Sagredo A, Garreras-Sureda A, Gutierrez D, Valls C, Acosta-Alvea D, Campos G, Alvarez A, Godoy P, Walter P, Glavic A, Kroemer G, Hetz C. Genotoxic stress triggers the selective activation of IRE1α-dependent RNA decay to modulate the DNA damage response. Nat CommunIn press

2019

  • Zitvogel L, Kroemer G. Immunostimulatory gut bacteria. Science. 2019 Nov 29;366(6469):1077-1078. 
  • Notomi S, Ishihara K, Efstathiou NE, Lee JJ, Hisatomi T, Tachibana T, Konstantinou EK, Ueta T, Murakami Y, Maidana DE, Ikeda Y, Kume S, Terasaki H, Sonoda S, Blanz J, Young L, Sakamoto T, Sonoda KH, Saftig P, Ishibashi T, Miller JW, Kroemer G*, Vavvas DG. (*Corresponding author). Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23724-23734. 
  • Chen G, Xie W, Nah J, Sauvat A, Liu P, Pietrocola F, Sica V, Carmona-Gutierrez D, Zimmermann A, Pendl T, Tadic J, Bergmann M, Hofer SJ, Domuz L, Lachkar S, Markaki M, Tavernarakis N, Sadoshima J, Madeo F, Kepp O, Kroemser G. 3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB. EMBO Mol Med. 2019 Nov 7;11(11):e10469
  • Bravo-San Pedro JM, Sica V, Martins I, Pol J, Loos F, Maiuri MC, Durand S, Bossut N, Aprahamian F, Anagnostopoulos G, Niso-Santano M, Aranda F, Ramírez-Pardo I, Lallement J, Denom J, Boedec E, Gorwood P, Ramoz N, Clément K, Pelloux V, Rohia A, Pattou F, Raverdy V, Caiazzo R, Denis RGP, Boya P, Galluzzi  L, Madeo F, Migrenne-Li S, Cruciani-Guglielmacci C, Tavernarakis N, López-Otín C, Magnan C, Kroemer G. Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity. Cell Metab. 2019 Oct 1;30(4):754-767.e9. 
  • Jacquelot N, Yamazaki T, Roberti MP, Duong CPM, Andrews MC, Verlingue L, Ferrere G, Becharef S, Vétizou M, Daillère R, Messaoudene M, Enot DP, Stoll G, Ugel S, Marigo I, Foong Ngiow S, Marabelle A, Prevost-Blondel A, Gaudreau PO, Gopalakrishnan V, Eggermont AM, Opolon P, Klein C, Madonna G, Ascierto PA, Sucker A, Schadendorf D, Smyth MJ, Soria JC, Kroemer G*, Bronte V, Wargo J, Zitvogel L. (*Corresponding author). Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade. Cell Res. 2019 Oct;29(10):846-861
  • Paoletti A, Allouch A, Caillet M, Saïdi H, Subra F, Nardacci R, Wu Q, Muradova Z, Voisin L, Raza SQ, Law F, Thoreau M, Dakhli H, Delelis O, Poirier-Beaudouin B, Dereuddre-Bosquet N, Le Grand R, Lambotte O, Saez-Cirion A, Pancino G, Ojcius DM, Solary E, Deutsch E, Piacentini M, Gougeon ML, Kroemer G*, Perfettini JL. (*Senior author). HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry. Cell Rep. 2019 Sep 24;28(13):3381-3394.e7
  • Kroemer G, Zitvogel L. Leptin-Producing Oncolytic Virus Makes Tumor-Infiltrating T Cells Fit, Not Fat. Immunity. 2019 Sep 17;51(3):423-425. 
  • Stekovic S, Hofer SJ, Tripolt N, Aon MA, Royer P, Pein L, Stadler JT, Pendl T, Prietl B, Url J, Schroeder S, Tadic J, Eisenberg T, Magnes C, Stumpe M, Zuegner E, Bordag N, Riedl R, Schmidt A, Kolesnik E, Verheyen N, Springer A, Madl T, Sinner F, de Cabo R, Kroemer G, Obermayer-Pietsch B, Dengjel J, Sourij H, Pieber TR, Madeo F. Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans. Cell Metab. 2019 Sep 3;30(3):462-476.e5. 
  • Zimmermann A, Kainz K, Hofer SJ, Bauer MA, Schroeder S, Dengjel J, Pietrocola  F, Kepp O, Ruckenstuhl C, Eisenberg T, Sigrist SJ, Madeo F, Carmona-Gutierrez D,  Kroemer G. 4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects. Autophagy. 2019 Sep;15(9):1662-1664. 
  • Zitvogel L, Kroemer G. Interferon-γ induces cancer cell ferroptosis. Cell Res. 2019 Sep;29(9):692-693. 
  • Yang H, Xia L, Chen J, Zhang S, Martin V, Li Q, Lin S, Chen J, Calmette J, Lu  M, Fu L, Yang J, Pan Z, Yu K, He J, Morand E, Schlecht-Louf G, Krzysiek R, Zitvogel L, Kang B, Zhang Z, Leader A, Zhou P, Lanfumey L, Shi M, Kroemer G*, Ma Y. (*Corresponding author). Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity. Nat Med. 2019 Sep;25(9):1428-1441. 
  • Deutsch E, Chargari C, Galluzzi L, Kroemer G. Optimising efficacy and reducing toxicity of anticancer radioimmunotherapy. Lancet Oncol. 2019 Aug;20(8):e452-e463.
  • Bárcena C, Valdés-Mas R, Mayoral P, Garabaya C, Durand S, Rodríguez F, Fernández-García MT, Salazar N, Nogacka AM, Garatachea N, Bossut N, Aprahamian F, Lucia A, Kroemer G, Freije JMP, Quirós PM, López-Otín C. Healthspan and lifespan  extension by fecal microbiota transplantation into progeroid mice. Nat Med. 2019 Aug;25(8):1234-1242.
  • Kroemer G, Zitvogel L. Leptin-Producing Oncolytic Virus Makes Tumor-Infiltrating T Cells Fit, Not Fat. Immunity. 2019 Sep 17;51(3):423-425. 
  • Yang H, Xia L, Chen J, Zhang S, Martin V, Li Q, Lin S, Chen J, Calmette J, Lu M, Fu L, Yang J, Pan Z, Yu K, He J, Morand E, Schlecht-Louf G, Krzysiek R, Zitvogel L, Kang B, Zhang Z, Leader A, Zhou P, Lanfumey L, Shi M, Kroemer G*, Ma Y. (*Corresponding author). Stress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity. Nat Med. 2019 Sep;25(9):1428-1441.
  • Jacquelot N, Yamazaki T, Roberti MP, Duong CPM, Andrews MC, Verlingue L, Ferrere G, Becharef S, Vétizou M, Daillère R, Messaoudene M, Enot DP, Stoll G, Ugel S, Marigo I, Foong Ngiow S, Marabelle A, Prevost-Blondel A, Gaudreau PO, Gopalakrishnan V, Eggermont AM, Opolon P, Klein C, Madonna G, Ascierto PA, Sucker A, Schadendorf D, Smyth MJ, Soria JC, Kroemer G*, Bronte V, Wargo J, Zitvogel L. (*Corresponding author). Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade. Cell Res. 2019 Sep 3. doi: 10.1038/s41422-019-0224-x.
  • Bravo-San Pedro JM, Sica V, Martins I, Pol J, Loos F, Maiuri MC, Durand S, Bossut N, Aprahamian F, Anagnostopoulos G, Niso-Santano M, Aranda F, Ramírez-Pardo I, Lallement J, Denom J, Boedec E, Gorwood P, Ramoz N, Clément K, Pelloux V, Rohia A, Pattou F, Raverdy V, Caiazzo R, Denis RGP, Boya P, Galluzzi L, Madeo F, Migrenne-Li S, Cruciani-Guglielmacci C, Tavernarakis N, López-Otín C, Magnan C, Kroemer G. Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity. Cell Metab. 2019 Oct 1;30(4):754-767.
  • Vitale I, Manic G, Coussens LM, Kroemer G*, Galluzzi L. (*Corresponding author). Macrophages and Metabolism in the Tumor Microenvironment. Cell Metab. 2019 Jul 2;30(1):36-50.
  • Rao S, Mondragón L, Pranjic B, Hanada T, Stoll G, Köcher T, Zhang P, Jais A, Lercher A, Bergthaler A, Schramek D, Haigh K, Sica V, Leduc M, Modjtahedi N, Pai TP, Onji M, Uribesalgo I, Hanada R, Kozieradzki I, Koglgruber R, Cronin SJ, She Z, Quehenberger F, Popper H, Kenner L, Haigh JJ, Kepp O, Rak M, Cai K, Kroemer G*, Penninger JM. (*Corresponding author). AIF-regulated oxidative phosphorylation supports lung cancer development. Cell Res. 2019 Jul;29(7):579-591. 
  • Lopez-Otín C, Kroemer G. Decelerating ageing and biological clocks by autophagy. Nat Rev Mol Cell Biol. 2019 Jul;20(7):385-386. 
  • Tang D, Kang R, Berghe TV, Vandenabeele P, Kroemer G. The molecular machinery of regulated cell death. Cell Res. 2019 May;29(5):347-364
  • Sica V, Bravo-San Pedro JM, Izzo V, Pol J, Pierredon S, Enot D, Durand S, Bossut N, Chery A, Souquere S, Pierron G, Vartholomaiou E, Zamzami N, Soussi T, Sauvat A, Mondragón L, Kepp O, Galluzzi L, Martinou JC, Hess-Stumpp H, Ziegelbauer K, Kroemer G*, Maiuri MC. (Corresponding author). Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate. Cell Rep. 2019 Apr 16;27(3):820-834.e9. 
  • Liu P, Zhao L, Pol J, Levesque S, Petrazzuolo A, Pfirschke C, Engblom C, Rickelt S, Yamazaki T, Iribarren K, Senovilla L, Bezu L, Vacchelli E, Sica V, Melis A, Martin T, Xia L, Yang H, Li Q, Chen J, Durand S, Aprahamian F, Lefevre D, Broutin S, Paci A, Bongers A, Minard-Colin V, Tartour E, Zitvogel L, Apetoh L, Ma Y, Pittet MJ, Kepp O, Kroemer G. Crizotinib-induced immunogenic cell death in non-small cell lung cancer. Nat Commun. 2019 Apr 2;10(1):1486. 
  • Madeo F, Carmona-Gutierrez D, Hofer SJ, Kroemer G. Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential. Cell Metab. 2019 Mar 5;29(3):592-610. 
  • Carmona-Gutierrez D, Zimmermann A, Kainz K, Pietrocola F, Chen G, Maglioni S, Schiavi A, Nah J, Mertel S, Beuschel CB, Castoldi F, Sica V, Trausinger G, Raml R, Sommer C, Schroeder S, Hofer SJ, Bauer MA, Pendl T, Tadic J, Dammbrueck C, Hu  Z, Ruckenstuhl C, Eisenberg T, Durand S, Bossut N, Aprahamian F, Abdellatif M, Sedej S, Enot DP, Wolinski H, Dengjel J, Kepp O, Magnes C, Sinner F, Pieber TR, Sadoshima J, Ventura N, Sigrist SJ, Kroemer G*, Madeo F. (*Corresponding author). The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species. Nat Commun. 2019 Feb 19;10(1):651. 
  • Villella VR, Venerando A, Cozza G, Esposito S, Ferrari E, Monzani R, Spinella  MC, Oikonomou V, Renga G, Tosco A, Rossin F, Guido S, Silano M, Garaci E, Chao YK, Grimm C, Luciani A, Romani L, Piacentini M, Raia V, Kroemer G*, Maiuri L. (*Corresponding author). A pathogenic role for cystic fibrosis transmembrane conductance regulator in celia disease. EMBO J. 2019 Jan 15;38(2). pii: e100101. 
  • Levine B, Kroemer G. Biological Functions of Autophagy Genes: A Disease Perspective. Cell. 2019 Jan 10;176(1-2):11-4

 

All-stars:

  • López-Soto A et al., Cancer-Induced Endoplasmic Reticulum Stress in T Cells Subverts Immunosurveillance. Cell Metab. 28, 803-805 (2018)
  • Galluzzi L et al., Linking cellular stress responses to systemic homeostasis. Nat Rev Mol Cell Biol. 19, 731-745 (2018)
  • Kroemer G et al., Carbotoxicity-Noxious Effects of Carbohydrates. Cell. 175, 605-614 (2018)
  • Boland B et al., Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing. Nat Rev Drug Discov. 17, 660-688 (2018)
  • Bárcena C et al., Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism. Cell Rep. 28, 2392-2403 (2018)
  • Li et al., PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism. Dev Cell. 46, 441-455 (2018)
  • Song X et al., AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System X(c)(-) Activity. Curr Biol. 28, 2388-2399 (2018)
  • Lebeaupin C et al., Bax inhibitor-1 protects from nonalcoholic steatohepatitis by limiting inositol-requiring enzyme 1 alpha signaling in mice. Hepatology. 68, 515-532 (2018)
  • Obrist F et al., Metabolic vulnerability of cisplatin-resistant cancers. EMBO J. 13, (2018)
  • Kang et al., Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis. Cell Host Microbe. 24, 97-108(2018)
  • Gomes-da-Silva LC et al., Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus. EMBO J. 37, (2018)
  • Routy B et al., The gut microbiota influences anticancer immunosurveillance and general health. Nat Rev Clin Oncol. 15, 382-396 (2018)
  • Song X et al., JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice. Gastroenterology. 154, 1480-1493 (2018)
  • Zitvogel L et al., The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies. Science. 23 1366-1370 (2018)
  • Porporato PE et al., Mitochondrial metabolism and cancer. Cell Res. 28 265-280 (2018)
  • Rybstein MD et al., The autophagic network and cancer. Nat Cell Biol. 20, 243-251 (2018)
  • Pietrocola F et al., Aspirin Recapitulates Features of Caloric Restriction. Cell Rep. 22, 2395-2407 (2018)
  • Abrahão J et al., Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere. Nat Commun. 9, 749 (2018)
  • Madeo F et al., Spermidine in health and disease. Science. 26, 6374 (2018)
  • Routy B et al., Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors. Science. 359, 91-97 (2018)
  • Bantug GR, et al., The spectrum of T cell metabolism in health and disease. Nat Rev Immunol.18, 19-34 (2018)
  • Fridman WH et al., The immune contexture in cancer prognosis and treatment. Nat Rev Clin Oncol. 14, 717-734 (2017)
  • Xie Y et al., Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma. Gastroenterology. 153, 1429-1443 (2017)
  • Jacquelot N et al., Predictors of responses to immune checkpoint blockade in advanced melanoma. Nat Commun. 8, 592 (2017
  • Xie Y, et al., The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity. Cell Rep. 20, 1692-1704 2017
  • Zitvogel L et al., Anticancer effects of the microbiome and its products. Nat Rev Microbiol. 15, 465-478 2017
  • Zitvogel L et al., Nutrition, inflammation and cancer. Nat Immunol. 18, 843-850 (2017)
  • Galluzzi L et al., Molecular definitions of autophagy and related processes. EMBO J. 36, 1811-1836 (2017)
  • Galluzzi L et al .,Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles. Nat Rev Drug Discov. 16, 487-511 (2017)
  • Esteban-Martínez L et al., Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 36, 1688-1706 (2017)
  • Vitale I et al., DNA Damage in Stem Cells. Mol Cell. 66, 306-319 (2017)
  • L Romani et al., Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis. Nat Med. 23 590-600 (2017)
  • Galluzzi L et al., Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy. Nat Rev Clin Oncol. 14, 247-258 (2017)
  • Galluzzi L et al., Immunogenic cell death in cancer and infectious disease. Nat Rev Immunol. 17, 97-111 (2017)
  • Galluzzi L et al., Necroptosis: Mechanisms and Relevance to Disease. Annu Rev Pathol. 12, 103-130 (2017)
  • Sixt BS et al., The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs. Cell Host Microbe 21, 113-121 (2017)
  • T. Eisenberg et al., Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat Med 12, 1428-1438 (2016).
  • C. Lopez-Otin, L. Galluzzi, J. M. Freije, F. Madeo, G. Kroemer, Metabolic Control of Longevity. Cell 166, 802-821 (2016).
  • F. Pietrocola et al., Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance. Cancer Cell 30, 147-160 (2016).
  • L. Zitvogel, M. Ayyoub, B. Routy, G. Kroemer, Microbiome and Anticancer Immunosurveillance. Cell 165, 276-287 (2016).
  • L. Galluzzi, A. Buque, O. Kepp, L. Zitvogel, G. Kroemer, Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents. Cancer Cell 28, 690-714 (2015).
  • M. Vetizou et al., Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota. Science 350, 1079-1084 (2015).
  • E. Vacchelli et al., Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1. Science 350, 972-978 (2015).
  • G. Kroemer, L. Senovilla, L. Galluzzi, F. Andre, L. Zitvogel, Natural and therapy-induced immunosurveillance in breast cancer. Nat Med 21, 1128-1138 (2015).
  • M. Gentili et al., Transmission of innate immune signaling by packaging of cGAMP in viral particles. Science 349, 1232-1236 (2015).
  • L. Zitvogel, G. Kroemer, CANCER. A p53-regulated immune checkpoint relevant to cancer. Science 349, 476-477 (2015).
  • L. Zitvogel, G. Kroemer, Cancer: Antibodies regulate antitumour immunity. Nature 521, 35-37 (2015).
  • L. Zitvogel, G. Kroemer, CD103+ dendritic cells producing interleukin-12 in anticancer immunosurveillance. Cancer Cell 26, 591-593 (2014).
  • L. Galluzzi, F. Pietrocola, B. Levine, G. Kroemer, Metabolic control of autophagy. Cell 159, 1263-1276 (2014). Sistigu et al., Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy. Nat Med 20, 1301-1309 (2014).
  • D. R. Green, L. Galluzzi, G. Kroemer, Cell biology. Metabolic control of cell death. Science 345, 1250256 (2014).
  • L. Galluzzi, J. M. Bravo-San Pedro, G. Kroemer, Organelle-specific initiation of cell death. Nat Cell Biol 16, 728-736 (2014).
  • S. Viaud et al., The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science 342, 971-976 (2013).
  • Lopez-Otin, M. A. Blasco, L. Partridge, M. Serrano, G. Kroemer, The hallmarks of aging. Cell 153, 1194-1217 (2013).
  • L. Senovilla et al., An immunosurveillance mechanism controls cancer cell ploidy. Science 337, 1678-1684 (2012).
  • M. Michaud et al., Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice. Science 334, 1573-1577 (2011).
  • L. Zitvogel, G. Kroemer, Anticancer effects of imatinib via immunostimulation. Nat Med 17, 1050-1051 (2011).
  • C. Rubinsztein, G. Marino, G. Kroemer, Autophagy and aging. Cell 146, 682-695 (2011).
  • R. Green, L. Galluzzi, G. Kroemer, Mitochondria and the autophagy-inflammation-cell death axis in organismal aging. Science 333, 1109-1112 (2011).
  • N. F. Delahaye et al., Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. Nat Med 17, 700-707 (2011).
  • Madeo, N. Tavernarakis, G. Kroemer, Can autophagy promote longevity? Nat Cell Biol 12, 842-846 (2010).
  • L. Zitvogel, G. Kroemer, Targeting dendritic cell metabolism in cancer. Nat Med 16, 858-859 (2010).
  • L. Zitvogel, O. Kepp, G. Kroemer, Decoding cell death signals in inflammation and immunity. Cell 140, 798-804 (2010).
  • T. Eisenberg et al., Induction of autophagy by spermidine promotes longevity. Nat Cell Biol 11, 1305-1314 (2009).
  • Ghiringhelli et al., Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med 15, 1170-1178 (2009).
  • D. R. Green, G. Kroemer, Cytoplasmic functions of the tumour suppressor p53. Nature 458, 1127-1130 (2009).
  • L. Galluzzi, G. Kroemer, Necroptosis: a specialized pathway of programmed necrosis. Cell 135, 1161-1163 (2008).
  • Kroemer, J. Pouyssegur, Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 13, 472-482 (2008).
  • E. Tasdemir et al., Regulation of autophagy by cytoplasmic p53. Nat Cell Biol 10, 676-687 (2008).
  • B. Levine, G. Kroemer, Autophagy in the pathogenesis of disease. Cell 132, 27-42 (2008).
  • B. Levine, G. Kroemer, SnapShot: Macroautophagy. Cell 132, 162 e161-162 e163 (2008).
  • J. A. Pospisilik et al., Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes. Cell 131, 476-491 (2007).
  • L. Apetoh et al., Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med 13, 1050-1059 (2007).
  • L. Galluzzi, G. Kroemer, Mitochondrial apoptosis without VDAC. Nat Cell Biol 9, 487-489 (2007).
  • M. Obeid et al., Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med 13, 54-61 (2007).
  • J. Taieb et al., A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med 12, 214-219 (2006).
  • Kroemer, S. J. Martin, Caspase-independent cell death. Nat Med 11, 725-730 (2005).
  • D. R. Green, G. Kroemer, The pathophysiology of mitochondrial cell death. Science 305, 626-629 (2004).
  • L. Perfettini, R. T. Kroemer, G. Kroemer, Fatal liaisons of p53 with Bax and Bak. Nat Cell Biol 6, 386-388 (2004).
  • M. Penninger, G. Kroemer, Mitochondria, AIF and caspases--rivaling for cell death execution. Nat Cell Biol 5, 97-99 (2003).
  • F. Ferri, G. Kroemer, Organelle-specific initiation of cell death pathways. Nat Cell Biol 3, E255-263 (2001).
  • Ravagnan et al., Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol 3, 839-843 (2001).
  • Joza et al., Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 410, 549-554 (2001).
  • J. M. Bruey et al., Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat Cell Biol 2, 645-652 (2000).
  • C. Brenner, G. Kroemer, Apoptosis. Mitochondria--the death signal integrators. Science 289, 1150-1151 (2000). G. Kroemer, J. C. Reed, Mitochondrial control of cell death. Nat Med 6, 513-519 (2000).
  • K. F. Ferri, G. Kroemer, Control of apoptotic DNA degradation. Nat Cell Biol 2, E63-64 (2000).
  • Zamzami, G. Kroemer, Condensed matter in cell death. Nature 401, 127-128 (1999).
  • S. A. Susin et al., Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397, 441-446 (1999).
  • Marzo et al., Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 281, 2027-2031 (1998).
  • G. Kroemer, The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 3, 614-620 (1997).

Among more than 1000 scientific publications. For a full list please check here.


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